Searchable abstracts of presentations at key conferences in endocrinology

ea0039ep90 | Miscellaneous/other | BSPED2015

Case of raised creatinine in a newborn with congenital hyperinsulinism: diazoxide induced acute kidney injury

Godinho Felvira , Lewin Rebecca , Park Julie , Losa Ignatius

Background: Congenital hyperinsulinism (CHI) is the result of unregulated insulin secretion from the pancreatic β-cells leading to severe hypoglycaemia.1 Diazoxide is effective in virtually all forms of CHI except in those due to recessive (and some dominant) inactivating mutations in ABCC8 and KCNJ11 and in patients with focal CHI.2 We report a case of CHI with acute kidney injury secondary to diazoxide.Case ...